More on RESVERATROL
Natural Antibiotic and Powerful Antioxidant

Resveratrol is a natural antibiotic (phytoalexin) produced by plants as part of their defensive arsenal against invading pathogens. Resveratrol is also one of about 300 salvestrols, natural anti-malignancy compounds, found in all living cells. Malignant cells contain an enzyme, CYP1B1, which combines with salvestrol to produce a toxin which kills the abnormal or malignant cell. 

Resveratrol is found in significant amounts in grapes and peanuts. In grapes, Resveratrol is concentrated in the skin.  It is also found in Japanese Knotweed.

  •  180 grams of boiled peanuts contains .32 to 1.28 mg of Resveratrol
  •  160 grams of red grapes contains .24 to 1.25 mg of Resveratrol
In animal experiments on rats and mice, Resveratrol was found to have very positive effects against cancer and inflammation.  It was found to lower blood-sugar levels and to promote cardiovascular health.  Specifically the findings pointed to:
  •  Lower cholesterol levels
  •  Reduced inflammation of heart tissue
  •  Better bone health, increased density, thickness, volume and mineral content
  •  Reduced cataract formation
  •  Enhanced balance and motor nerve coordination
  •  Improved liver function, skeletal muscle and reduced fatty tissue deposits
(These results were reported on July 3, 2008 by the US National Institute on Aging, NIH News, U.S. Dept of Health and Human Services)
Other animal experiments have shown that Resveratrol has life-extension benefits; commensurate with the results seen from extreme calorie-restrictive diets.

These animal experiments have made Resveratrol a hot topic. It's been seen by some as a possible miracle vitamin for preventing chronic degenerative diseases and as a supplement which could slow down the aging process.

It has yet to be proven that the studies conducted on animals will carry over to human populations. Nonetheless, these studies have shown that the action of Resveratrol on cell metabolism reduces the effects of oxidation. This means that Resveratrol has strong anti-oxidant properties and can reduce cellular free radical cell damage.
 
Some human studies have shown that Resveratrol has anti-cancer properties. Resveratrol has been proven to interrupt cancer growth:

"Because resveratrol (trans-3,4',5-trihydroxystilbene) is reported to display anti-tumor activities on a variety of human cancer cells, we investigated the effects of this natural compound on myeloma and bone cells. We found that resveratrol reduces dose-dependently the growth of myeloma cell lines (RPMI 8226 and OPM-2) by a mechanism involving cell apoptosis...Taken together, these results suggest that resveratrol or its derivatives deserve attention as potential drugs for treating multiple myeloma."
Resveratrol Inhibits Myeloma Cell Growth, Prevents Osteoclast Formation and Promotes Osteoblast Differentiation; Patrice Boissy, T. L. Andersen, B. M. Abdallah, M. Kassem, T. Plesner and Jean-Marie Delaissé; Cancer Research 65, 9943-9952, November 1, 2005 © 2005 American Association for Cancer Research
Current research indicates that getting Resveratrol into your system is desirable.  Consuming enough wine or anything else in the quantities needed to show an appreciable elevation in the blood is not feasible.
 
Supplementation in normal form leads to either low absorption of low bio-availability.  Resveratrol taken normally has a bio-availability rate of about 5% of the dosage taken.  With liposomal formulation, we get over 85% percent bio-availability.

"The dietary polyphenol resveratrol has been shown to have chemopreventive activity against cardiovascular disease and a variety of cancers in model systems, but it is not clear whether the drug reaches the proposed sites of action in vivo after oral ingestion, especially in humans....Extremely rapid sulfate conjugation by the intestine/liver appears to be the rate-limiting step in resveratrol's bioavailability."

HIGH ABSORPTION BUT VERY LOW BIOAVAILABILITY OF ORAL RESVERATROL IN HUMANS; Thomas Walle, Faye Hsieh, Mark H. DeLegge, John E. Oatis, Jr., and U. Kristina Walle; Drug Metabolism and Disposition  First published on August 27, 2004

We have charted actual levels of Resveratrol circulating in the blood stream for over 6 hours after a typical dosage of our Liposomal Resveratrol single nutrient formula.

By creating minute-sized particles of Resveratrol and encapsulating the nutrient in liposomes, we offer a safe and effective way to get all the benefits of supplemental Resveratrol in a liquid formula you can take orally.  

Benefits of Resveratrol  
  • Powerful Antioxidant
  • Anti-Carcinogenic - has properties to prevent and actually reverse some cancers
  • Central Nervous System - regulates hormones
  • Natural Blood Thinning Agent
  • Strengthens the Heart and Cardiovascular System - lowers risk of heart disease
  • Rebuilds the Liver
  • Reduces the risk of Alzheimer's Disease
  • Helps in Recovery from Strokes
  • Aids in Rehabilitation from Injuries and Trauma of Central Nervous System
  • A Potential Aid to Anti-Aging and Life Extension
We offer Resveratrol in 3 of our Liposomal Formulas:

Besides the Single Nutrient Formula, Resveratrol is an ingredient in our CAN-HELP and AGE-LESS Liposomal Nutritional Support Formulas.

Normal dosage is one tablespoon, which contains:
500 mg Resveratrol

Normal dosage is 1 ounce (2 tablespoons), which contains:

   100 mg Resveratrol
   100 mg Glutathione
3,333 mg Vitamin C
   100 mg CoQ10
   100 mg Curcumin
  100 mg Vitamin B1 
  100 mg
Vitamin B6
  100 mcg Vitamin B12
      5 mcg Folic Acid


Although CAN-HELP has been formulated to offer anti-cancer nutritional support for cancer patients, this is an excellent anti-oxidant formula that can be used by anyone at a reduced dosage for general nutritional support.

Normal dosage is 1 ounce (2 Tablespoons), which contains:

  250 mg Resveratrol
1500 mg Vitamin C
 360 mg Milk Thistle
  250 mg Artichoke Extract
    25 mg CoQ10
    10 mg Cascara Sagrata
   
25 mg Vitamin B1
    25 mg Vitamin B6
 100 mcg Vitamin B12
     5 mcg Folate (Folic Acid



Any one of these formulas can help you enjoy the many benefits of Resveratrol today.  Get the dosage, the absorption and the bio-availability of Resveratrol your cells need to make a difference in your health and in your future.